ELECTRO-OSMOTIC FLOW THROUGH CLOSED-OPEN-CLOSED MICROCHANNELS: AN APPROACH TO HYPHENATION OF CAPILLARY ELECTROPHORESIS AND MALDI
2006 (English)In: 19th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2006), IEEE conference proceedings, 2006, 406-409 p.Conference paper (Refereed)
We suggest electro-osmotic driven flow (EOF) through closed-open-closed microchannels as a novel approach for spatial sample separation using capillary electrophoresis (CE) prior to matrix assisted laser desorption/ionization mass spectroscopy (MALDI-MS). For this purpose we built a system consisting of the series Coupling of a closed fused silica capillary for separation, a microfabricated open microcanal for future MS detection and a second closed fused silica capillary for downstream liquid collection. This work verifies the EOF transport of a peptide sample in such a system with low dispersion.
Place, publisher, year, edition, pages
IEEE conference proceedings, 2006. 406-409 p.
, Proceedings: IEEE Micro Electro Mechanical Systems Workshop, ISSN 1084-6999
Assisted-laser-desorption/ionization, mass-spectrometry, ms
IdentifiersURN: urn:nbn:se:kth:diva-9073DOI: 10.1109/MEMSYS.2006.1627822ISI: 000236994500102ScopusID: 2-s2.0-33750139065ISBN: 978-078039475-9OAI: oai:DiVA.org:kth-9073DiVA: diva2:14628
19th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2006), Istanbul, TURKEY, 22-26 Jan, 2006
QC 201009162006-02-102006-02-102015-06-03Bibliographically approved