Extended elasto-inertial microfluidics for high throughput separation in low aspect ratio spiral microchannels
2020 (English)In: 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, Chemical and Biological Microsystems Society , 2020, p. 1401-1402Conference paper, Published paper (Refereed)
Abstract [en]
Manipulation of particles and cells in viscoelastic fluids has received substantial interest because this phenomenon provides high-quality focusing. Here we present an enhanced particle focusing and separation in spiral channels, at a ten-fold increase of Reynolds number as compared to current state of the art elasto-inertial microfluidics and report stable particle focusing in spiral low aspect ratio channels at flow rates two magnitudes higher than that previously reported at a high throughput of 2 mL/min is demonstrated with an separation efficiency of 99% for the 15-micron and 91% for the 10-micron particles is demonstrated.
Place, publisher, year, edition, pages
Chemical and Biological Microsystems Society , 2020. p. 1401-1402
Keywords [en]
Elasto-inertial, PEO, Spiral channel, Focusing, Microfluidics, Molecular biology, Polyethylene oxides, Reynolds number, Inertial microfluidics, Low aspect ratio, Particle focusing, Separation efficiency, State of the art, Vis-coelastic fluids, Aspect ratio
National Category
Fluid Mechanics Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Identifiers
URN: urn:nbn:se:kth:diva-301113Scopus ID: 2-s2.0-85079610221OAI: oai:DiVA.org:kth-301113DiVA, id: diva2:1594319
Conference
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, Savannah, 22-26 October 2017
Note
Not duplicate with DiVA 1082892
QC 20210915
2021-09-152021-09-152025-02-09Bibliographically approved