Due to increased environmental issues and for economic reasons, the automotive industry intensifies the research towards energy efficient driving, without though eglecting the aspects of comfort and vehicle handling. In this direction, efforts of modeling and minimising tyre wear, one of the main non-exhaust traffic related sources, are investigated in the literature. In this work, the emphasis is on the optimisation of suspension and tyre parameters for minimising tyre wear while the vehicle is driving on different road surfaces. However, as comfort and vehicle handling are still important criteria in the design process, they are also included as objectives by configuring a multi-objective optimisation problem with all of the above objectives. The aim is to investigate how tyre wear behaves with regards to comfort and vehicle handling, and where the optimum design variables have converged trying to compromise the above objectives under different road roughness profiles.