An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogelsShow others and affiliations
2021 (English)In: Polymer Chemistry, ISSN 1759-9954, E-ISSN 1759-9962, Vol. 12, no 20, p. 2987-2991Article in journal (Refereed) Published
Abstract [en]
We present here a new insight into the chemical reactivity and bioactivity of dopamine (DA) and gallic acid (GA) and their hyaluronic acid (HA) conjugates. Our data suggest that HA-GA scaffolds are superior to HA-DA, with higher oxidation kinetics, improved tissue adhesive properties, and radical scavenging ability with a lower pro-inflammatory response. This journal is
Place, publisher, year, edition, pages
Royal Society of Chemistry (RSC) , 2021. Vol. 12, no 20, p. 2987-2991
Keywords [en]
Adhesives, Amines, Organic acids, Scaffolds (biology), Dopamine, Gallic acids, Hyaluronic acid hydrogels, Inflammatory response, Oxidation kinetics, Phenolic hydroxyl, Radical scavenging, Tissue adhesives, Hyaluronic acid
National Category
Polymer Chemistry Medical Materials Food Science
Identifiers
URN: urn:nbn:se:kth:diva-309633DOI: 10.1039/d1py00013fISI: 000650203600001Scopus ID: 2-s2.0-85106607738OAI: oai:DiVA.org:kth-309633DiVA, id: diva2:1643279
Note
QC 20220309
2022-03-092022-03-092025-02-09Bibliographically approved