We present a numerical study of emulsions in homogeneous and isotropic turbulence (HIT) at Re-lambda = 137. The problem is addressed via direct numerical simulations, where the volume of fluid is used to represent the complex features of the liquid-liquid interface. We consider a mixture of two iso-density fluids, where fluid properties are varied with the goal of understanding their role in turbulence modulation, in particular the volume fraction (0.03 < alpha < 0.5), viscosity ratio (0.01 < mu(d)/mu