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New Views of Old Proteins: Clarifying the Enigmatic Proteome
Pacific Northwest Natl Lab, Environm Mol Sci Lab, Richland, WA 99354 USA..
Inova Hlth Syst, Inova Womens Serv Line, Falls Church, VA USA..ORCID iD: 0000-0003-4742-3281
Med Univ South Carolina, Cell & Mol Pharmacol & Expt Therapeut, Charleston, SC USA..ORCID iD: 0000-0002-6285-6440
Univ Calif Berkeley, Dept Bioengn, Berkeley, CA USA..ORCID iD: 0000-0002-6906-2985
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2022 (English)In: Molecular & Cellular Proteomics, ISSN 1535-9476, E-ISSN 1535-9484, Vol. 21, no 7, article id 100254Article in journal (Refereed) Published
Abstract [en]

All human diseases involve proteins, yet our current tools to characterize and quantify them are limited. To better elucidate proteins across space, time, and molecular composition, we provide a >10 years of projection for technologies to meet the challenges that protein biology presents. With a broad perspective, we discuss grand opportunities to transition the science of proteomics into a more propulsive enterprise. Extrapolating recent trends, we describe a next generation of approaches to define, quantify, and visualize the multiple dimensions of the proteome, thereby transforming our understanding and interactions with human disease in the coming decade.

Place, publisher, year, edition, pages
Elsevier BV , 2022. Vol. 21, no 7, article id 100254
National Category
Biological Sciences
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URN: urn:nbn:se:kth:diva-316137DOI: 10.1016/j.mcpro.2022.100254ISI: 000830169700001PubMedID: 35654359Scopus ID: 2-s2.0-85133650597OAI: oai:DiVA.org:kth-316137DiVA, id: diva2:1686494
Note

QC 20220810

Available from: 2022-08-10 Created: 2022-08-10 Last updated: 2022-08-10Bibliographically approved

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Lundberg, Emma

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