The rapid advances of information technology have pushed society into the fourth industrial revolution (I4.0). It requires an integration of value chain organization and management across the product lifecycle driven by the Internet industrialization, industrial digitalization and intellectualization, and industrial integration. PLM is the business activity of managing a company's products from the idea of product development to the end of product life. It aims to seamlessly manage all products, information, and knowledge generated throughout the product's lifecycle in order to achieve business competitiveness. Blockchain is an emerging technology that brings transparency to opaque systems, verifiability, and immutability to transactions and processes, which gives it the potential to drive I4.0 revolution. This chapter will demonstrate the real-world applicability of blockchain potential using existing industrial case studies. Besides, an industrial blockchain-based PLM framework is introduced to facilitate data exchange and service sharing in the product lifecycle.