kth.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Neural Correlates of Parkinson’s Disease Motor Symptoms: A pipeline for exploration of correlation between neural and kinematic data
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH).
2022 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesisAlternative title
Neurala korrelater av motoriskasymptom vid Parkinsons sjukdom : En pipeline för utforskningav korrelationen mellan neurala (Swedish)
Abstract [en]

Parkinson’s Disease (PD) is a neurodegenerative disorder, within this categoryof diseases it is among the most prevalent worldwide. The etiology of PD isbased in progressive deterioration of neural tissue in the basal ganglia (neuronalnuclei located at the base of the cerebrum) and their related structures. Current research is focusing on treatment approaches to either enhance or replaceexisting pharmaceutical treatment approaches, such as dopamine replacementtherapy. In this project, the focus was on finding correlates between movementdata and neurological signals to provide insight into potential biomarkers forcomplex motor symptoms of PD. This will in turn provide a starting point forspecifically targeted closed-loop neural stimulation that alleviates these symptoms. Although the data available at the time of this thesis did not providesufficient insight to derive a conclusion on the neural correlates, a pipeline wasdeveloped, which analyzes and synchronizes kinematic and neural data and willenable further exploration as additional data is obtained.

Place, publisher, year, edition, pages
2022. , p. 33
Series
TRITA-CBH-GRU ; 2022:108
Keywords [en]
Parkinson’s Disease, neural modulation, neurodegenerative disorders, DBS, DCS, closed-loop neural stimulation
National Category
Medical Engineering
Identifiers
URN: urn:nbn:se:kth:diva-319109OAI: oai:DiVA.org:kth-319109DiVA, id: diva2:1698780
External cooperation
Charité – Universitätsmedizin Berlin
Subject / course
Medical Engineering
Educational program
Master of Science in Engineering - Medical Engineering
Supervisors
Examiners
Available from: 2022-10-11 Created: 2022-09-26 Last updated: 2022-10-11Bibliographically approved

Open Access in DiVA

fulltext(7263 kB)213 downloads
File information
File name FULLTEXT01.pdfFile size 7263 kBChecksum SHA-512
ad4572bd6613d572879a2375142e11337c7e736719946f9ba5821607f4a7366a9afc52eb09ad798c02e92af6fc373aea5b587e4ed37612d35930743cb39f5d39
Type fulltextMimetype application/pdf

By organisation
School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH)
Medical Engineering

Search outside of DiVA

GoogleGoogle Scholar
Total: 220 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

urn-nbn

Altmetric score

urn-nbn
Total: 245 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf