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Construction of Phenanthridinone Skeletons through Palladium-Catalyzed Annulation
School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthesis for Functional Materials Jiangsu Normal University, Xuzhou, Jiangsu 221116, China, Jiangsu.
School of Chemistry and Materials Science, Jiangsu Key Laboratory of Green Synthesis for Functional Materials Jiangsu Normal University, Xuzhou, Jiangsu 221116, China, Jiangsu.
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Chemistry, Organic chemistry.ORCID iD: 0000-0002-7249-7437
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Chemistry. Tomsk Polytechnic University, Lenin Avenue 30, 634050 Tomsk, Russia, Lenin Avenue 30.
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2023 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 88, no 17, p. 12738-12743Article in journal (Refereed) Published
Abstract [en]

Herein, a straightforward synthetic approach for the construction of phenanthridin-6(5H)-one skeletons is disclosed. The developed protocol relies on palladium catalysis, providing controlled access to a range of functionalized phenanthridin-6(5H)-ones in 59-88% yields. Furthermore, plausible reaction pathways are proposed based on mechanistic experiments.

Place, publisher, year, edition, pages
American Chemical Society (ACS) , 2023. Vol. 88, no 17, p. 12738-12743
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Organic Chemistry
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URN: urn:nbn:se:kth:diva-337794DOI: 10.1021/acs.joc.3c01429ISI: 001063447600001PubMedID: 37611263Scopus ID: 2-s2.0-85170059468OAI: oai:DiVA.org:kth-337794DiVA, id: diva2:1803338
Note

QC 20231009

Available from: 2023-10-09 Created: 2023-10-09 Last updated: 2023-10-09Bibliographically approved

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Shatskiy, AndreyStepanova, Elena VAlvey, Gregory R.Liu, JianquanKärkäs, Markus D.

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