Proton density fat fraction of calf muscles in children with cerebral palsy
2024 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE credits
Student thesisAlternative title
Protondensitetsfettfraktion i vadmuskler hos barn med cerebral pares (Swedish)
Abstract [en]
Cerebral Palsy (CP) a neuromotor disorder that leads to abnormal development of movement, muscle tone and posture and the chance of CP among the newborn is around 2.08‰. This study focuses on studying the spatial distribution pattern of intramuscular fat of the calf muscle in children with CP. Based on the Magnetic Resonance Imaging (MRI) scans from patients and the controlgroup, the 3D model of each muscle can be reconstructed, as well as the quantification of the fat distribution of different segments. Besides the average Fat Fraction (FF), the spatial distribution of Proton Density Fat Fraction (PDFF) of the muscles in interest are also evaluated.
Abstract [sv]
(CP) Cerebral Palsy är en neuromotorisk störning som leder till avvikande utveckling avrörelse, muskeltonus och hållning, och risken för CP bland nyfödda ligger på cirka 2,08‰. Denna studie fokuserar på att undersöka det rumsliga distributionsmönstret av intramuskulärt fett i vadmusklerna hos barn med CP.Baserat på MRI (Magnetic Resonance Imaging)-skanningar från patienter och kontrollgruppen kan 3D-modell av varje muskel rekonstrueras, liksom kvantifieringen av fettfördelningeni olika segment. Förutom genomsnittlig FF (Fat Fraction) utvärderas även den rumsliga distributionen av PDFF (Proton Density Fat Fraction) för musklerna av intresse.
Place, publisher, year, edition, pages
2024. , p. 97
Series
TRITA-CBH-GRU ; 2024:084
Keywords [en]
Proton Density Fat Fraction, Cerebral Palsy, Magnetic resonance imaging, Medial Gastrocnemius, Lateral Gastrocnemius, Soleus, Tibialis Anterior
National Category
Medical Engineering Radiology, Nuclear Medicine and Medical Imaging Sport and Fitness Sciences Neurology
Identifiers
URN: urn:nbn:se:kth:diva-352141OAI: oai:DiVA.org:kth-352141DiVA, id: diva2:1891176
Subject / course
Medical Engineering
Educational program
Master of Science - Medical Engineering
Supervisors
Examiners
2024-09-032024-08-212025-02-11Bibliographically approved