This thesis project explores the design, development, and evaluation of innovative end-effectors for a multi-arm robotic platform within the Moonshot Research & Development Program. Focusing on precise manipulation of biological samples, the study integrates comprehensive literature review, task analysis, iterative design, prototyping, and rigorous testing methodologies. Key improvements in weight reduction, force enhancement, precision, modularity, and compatibility with existing robotic systems were achieved through the application of precision engineering principles. Quantitative tests demonstrated significant performance enhancements in cutting and grasping tasks compared to previous designs. Notably, the new scissor unit cut through 6 layers of paper and handled thicker rubber sheets and gauze layers, while the new tweezer unit more than doubled its grip strength. Furthermore, a teleoperated frog manipulation experiment validated these advancements, showcasing the platform's capability for delicate biological tasks. The findings underscore the potential of these innovations to advance robotic manipulation in biological research and medical procedures, suggesting avenues for future refinement and application.