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Validation of an iterative reconstruction for a mobile tomographic gamma camera system - The Cardiotom
KTH, School of Technology and Health (STH), Medical Engineering.ORCID iD: 0000-0001-5919-3554
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2007 (English)In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, ISSN 0168-9002, E-ISSN 1872-9576, Vol. 580, no 2, 1097-1100 p.Article in journal (Refereed) Published
Abstract [en]

The Cardiotom is a mobile gamma camera that uses ectomography, an alternative method of acquisition to SPECT. It is designed for early diagnosis of myocardial and cerebral infarctions in the emergency room. Ectomography is a limited view angle method, using a rotating slant hole collimator and a stationary camera head, to acquire projection images. The aim of this work was to validate a fully 3D ML-EM iterative reconstruction algorithm for the Cardiotom. Validation measurements were performed with Tc-99m point sources. Resolution in the reconstructed volume was determined in X, Y. and Z directions from the point spread functions. The results were compared with the values for the formerly used filtered back projection (FBP). The new reconstruction algorithm provides greatly improved depth resolution with respect to the FBP method previously implemented on the Cardiotom. Furthermore, for clinical examinations, images can be available for interpretation within 15 min of the injection, therefore, valuable information can be obtained without delaying treatment of the patient. (c) 2007 Elsevier B.V. All rights reserved.

Place, publisher, year, edition, pages
2007. Vol. 580, no 2, 1097-1100 p.
Keyword [en]
medical imaging, image reconstruction, SPECT, gamma camera
National Category
Biomedical Laboratory Science/Technology
Identifiers
URN: urn:nbn:se:kth:diva-12059DOI: 10.1016/j.nima.2007.06.069ISI: 000250128000056Scopus ID: 2-s2.0-34548511146OAI: oai:DiVA.org:kth-12059DiVA: diva2:300788
Note
QC20100720Available from: 2010-03-01 Created: 2010-03-01 Last updated: 2017-12-12Bibliographically approved
In thesis
1. Applications of tomographic imaging in nuclear medicine
Open this publication in new window or tab >>Applications of tomographic imaging in nuclear medicine
2006 (English)Licentiate thesis, comprehensive summary (Other scientific)
Place, publisher, year, edition, pages
Stockholm: KTH, 2006. 29 p.
Series
Trita-FYS, ISSN 0280-316X ; 2006:63
National Category
Physical Sciences
Identifiers
urn:nbn:se:kth:diva-4187 (URN)
Presentation
2006-11-24, Sal FA32, AlbaNova univ. centrum, Roslagstullsbacken 21, Stockholm, 14:00 (English)
Opponent
Supervisors
Note
QC 20101125Available from: 2006-11-27 Created: 2006-11-27 Last updated: 2010-11-25Bibliographically approved
2. Software Solutions for Nuclear Imaging Systems in Cardiology, Small Animal Research and Education
Open this publication in new window or tab >>Software Solutions for Nuclear Imaging Systems in Cardiology, Small Animal Research and Education
2010 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The sensitivity for observing physiological processes makes nuclear imaging an important tool in medical diagnostics. Different types of nuclear imaging modalities, with emphasis on the software components and image reconstructions, are presented in this thesis:  the Cardiotom for myocardial heart studies at the Karolinska University Hospital, the small animal Positron Emission Tomograph (PET) scanners for research and the SPECT, PET, spiral CT and Cardiotom demonstrators for the Royal Institute of Technology medical imaging laboratory.

A modular and unified software platform has been developed for data representation, acquisition, visualization, reconstruction and presentation of the programs of the imaging devices mentioned above. The high performance 3D ML-EM and OS-EM iterative image reconstruction methods are implemented both on Cardiotom and miniPET scanners.

As a result, the in-slice resolution of the first two prototypes of the Cardiotom today is the same as the formerly used filtered back-projection, however the in-depth resolution is considerably increased. Another improvement due to the new software is the shorter time that is required for data acquisition and image reconstruction. The new electronics with the newly developed software ensure images for medical diagnosis within 10 minutes from the start ofthe examination. The first system from the standardized production of the Cardiotom cameras is in the test phase.

The performance parameters (sensitivity, spatial and energy resolution, coincidence time resolution) of the full ring mini PET camera are comparable to other small animal PETsystems.

Place, publisher, year, edition, pages
Stockholm: KTH, 2010. 75 p.
Series
Trita-STH : report, ISSN 1653-3836 ; 2010:1
National Category
Biomedical Laboratory Science/Technology
Identifiers
urn:nbn:se:kth:diva-12069 (URN)
Public defence
2010-03-19, KTH-Flemingsberg, Sal 3-221, Alfred Nobels Allé 10, Stockholm, 09:15 (English)
Opponent
Supervisors
Note
QC20100721Available from: 2010-03-02 Created: 2010-03-01 Last updated: 2010-07-21Bibliographically approved

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Valastyán, Iván

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