Label-free optical biosensing with slot-waveguides
2008 (English)In: Optics Letters, ISSN 0146-9592, E-ISSN 1539-4794, Vol. 33, no 7, 708-710 p.Article in journal (Refereed) Published
We demonstrate label-free molecule detection by using an integrated biosensor based on a Si3N4/SiO2 Slot-waveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/(ng/mm(2)) for the detection of anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm(2) for anti-BSA and BSA, respectively, limited by wavelength resolution.
Place, publisher, year, edition, pages
2008. Vol. 33, no 7, 708-710 p.
MICRORING RESONATORS; SENSOR
IdentifiersURN: urn:nbn:se:kth:diva-12209DOI: 10.1364/OL.33.000708ISI: 000255227000025ScopusID: 2-s2.0-42449116503OAI: oai:DiVA.org:kth-12209DiVA: diva2:305947