Dendritic oxazoline ligands in enantioselective palladium-catalyzed allylic alkylations
2002 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 67, no 23, 8197-8202 p.Article in journal (Refereed) Published
First to fourth generation dendritic substituents based on 2,2-bis(hydroxymethyl)propionic acid and (1R,2S,5R)-menthoxyacetic acid were attached to 2-(hydroxymethyl)pyridinooxazoline and his[4-(hydroxymethyl)oxazoline] compounds. The new ligands obtained were assessed in palladium-catalyzed allylic alkylations. The first type of ligands exhibited enantioselectivity similar to that of a benzoyl ester derivative, whereas the latter type of ligands afforded products with higher selectivity than the analogous benzoyl ester. The activity of the dendritic catalysts decreased with increasing generation.
Place, publisher, year, edition, pages
2002. Vol. 67, no 23, 8197-8202 p.
Alkylation, Catalysis, Catalysts, Esters, Palladium
IdentifiersURN: urn:nbn:se:kth:diva-13162DOI: 10.1021/jo0200116ISI: 000179110400033OAI: oai:DiVA.org:kth-13162DiVA: diva2:321565
QC 201006012010-06-012010-05-312010-10-26Bibliographically approved