Important structural factors controlling the conductance of DNA pairs in molecular junctions
2010 (English)In: The Journal of Physical Chemistry C, ISSN 1932-7447, E-ISSN 1932-7455, Vol. 114, no 33, 14240-14242 p.Article in journal (Refereed) Published
It has been demonstrated experimentally that DNA base pairs and sequences can be identified by measuring their current changes in metal junctions. We report here a first principles study on electron transport properties of DNA base pairs in gold metal junctions. It is found that the experimentally observed electrode-separation-width-dependent current changes of DNA base pairs are not due to the difference in number of hydrogen bonds involved in different base pairs as proposed in earlier experimental studies but caused by the difference in their stacking structures. It reveals that such an electronic read-out technique is not exact, but practically useful since the statistically favorable misaligned junctions do show distinct dependence on the character of the base pair.
Place, publisher, year, edition, pages
2010. Vol. 114, no 33, 14240-14242 p.
Base pairs, Current change, DNA base pairs, Experimental studies, First-principles study, Metal junctions, Molecular junction, Stacking structures, Structural factor
IdentifiersURN: urn:nbn:se:kth:diva-13854DOI: 10.1021/jp100798gISI: 000280961800039ScopusID: 2-s2.0-77955889117OAI: oai:DiVA.org:kth-13854DiVA: diva2:327766
QC 20120328. Updated from submitted to published.2010-06-302010-06-302012-03-28Bibliographically approved