Change search
ReferencesLink to record
Permanent link

Direct link
Bronchiectasis in persons with skin lesions resulting from arsenic in drinking water
KTH, School of Architecture and the Built Environment (ABE), Land and Water Resources Engineering, Environmental Geochemistry and Ecotechnology.ORCID iD: 0000-0003-4350-9950
Show others and affiliations
2005 (English)In: Epidemiology, ISSN 1044-3983, E-ISSN 1531-5487, Vol. 16, no 6, 760-765 p.Article in journal (Refereed) Published
Abstract [en]

Background: Arsenic is a unique human carcinogen in that it causes lung cancer by exposure through ingestion (in drinking water) as well as through inhalation. Less is known about nonmalignant pulmonary disease after exposure to arsenic in drinking water. Methods: We recruited 108 subjects with arsenic-caused skin lesions and 150 subjects without lesions from a population survey of over 7000 people in an arsenic-exposed region in West Bengal, India. Thirty-eight study participants who reported at least 2 years of chronic cough underwent high-resolution computed tomography (CT); these scans were read by investigators in India and the United States without knowledge of the presence or absence of skin lesions. Results: The mean ( +/- standard deviation) bronchiectasis severity score was 3.4 ( +/- 3.6) in the 27 participants with skin lesions and 0.9 ( +/- 1.6) in the 11 participants without these lesions. In subjects who reported chronic cough, CT evidence of bronchiectasis was found in 18 (67%) participants with skin lesions and 3 (27%) subjects without skin lesions. Overall, subjects with arsenic-caused skin lesions had a 10-fold increased prevalence of bronchiectasis compared with subjects who did not have skin lesions (adjusted odds ratio = 10; 95% confidence interval = 2.7-37). Conclusions: These results suggest that, in addition to being a cause of lung cancer, ingestion of high concentrations of arsenic in drinking water may be a cause of bronchiectasis.

Place, publisher, year, edition, pages
2005. Vol. 16, no 6, 760-765 p.
Keyword [en]
west-bengal, cancer mortality, bangladesh, india, children, bladder, adults
URN: urn:nbn:se:kth:diva-15131DOI: 10.1097/01.ede.0000181637.10978.e6ISI: 000232709500007ScopusID: 2-s2.0-27944491567OAI: diva2:333172
QC 20100525Available from: 2010-08-05 Created: 2010-08-05Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Bhattacharya, Prosun
By organisation
Environmental Geochemistry and Ecotechnology
In the same journal

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 29 hits
ReferencesLink to record
Permanent link

Direct link