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Improving reliability and performance of DNA microarrays
KTH, School of Biotechnology (BIO), Proteomics.
KTH, School of Biotechnology (BIO), Gene Technology.
2006 (English)In: Expert Review of Molecular Diagnostics, ISSN 1473-7159, Vol. 6, no 3, 481-492 p.Article, review/survey (Refereed) Published
Abstract [en]

A great many platforms and versions of the microarray technology, with different characteristics and applications, have been developed. This review will describe some key issues in reliability and performance with the two most commonly used platforms for gene expression analysis, in situ-synthesized oligonucleotide microarrays or GeneChip((R)) and spotted microarrays. Some recent advances and new applications within the field will be mentioned briefly.

Place, publisher, year, edition, pages
2006. Vol. 6, no 3, 481-492 p.
Keyword [en]
cDNA microarray, microarray, normalization, oligonucleotide microarray, probe, target, transcriptome, transcript profile, differentially-expressed genes, self-organizing maps, false discovery rate, messenger-rna, oligonucleotide arrays, cell-cycle, statistical-inference, escherichia-coli, cdna microarrays, global analysis
URN: urn:nbn:se:kth:diva-15714DOI: 10.1586/14737159.6.3.481ISI: 000237916000018ScopusID: 2-s2.0-33745941345OAI: diva2:333756
QC 20100525Available from: 2010-08-05 Created: 2010-08-05Bibliographically approved

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