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Testing and risk assessment of persistent and bioaccumulating chemical substances - Improvements within REACH?
KTH, School of Architecture and the Built Environment (ABE), Philosophy.
2006 (English)In: Human and Ecological Risk Assessment, ISSN 1080-7039, Vol. 12, no 4, 782-805 p.Article in journal (Refereed) Published
Abstract [en]

In the proposed new European chemicals regulations - the REACH system - the improved control of persistent and bioaccumulating substances is stated as one of the tasks being of particular importance. In this article, the reliability and validity of the scientific basis for identification of persistent ( P), bioaccumulating ( B), and toxic ( T) substances, and for assessing the risks that these substances may pose, are discussed. We have used the European Union risk assessment of pentabromodiphenyl ether, PentaBDE ( CAS 32534-81-9) as a study case in the analysis. It is concluded that for PBT substances there is room for development both with regard to test methodology and with regard to risk assessment procedures.

Place, publisher, year, edition, pages
2006. Vol. 12, no 4, 782-805 p.
Keyword [en]
REACH, risk assessment, PBT, vPvB, PentaBDE, CAS 32534-81-9, cytochrome-p450 activity, harpacticoid copepod, liver morphology, reproduction, constants, sediment, exposure, pbdes, water, fish
URN: urn:nbn:se:kth:diva-15977DOI: 10.1080/10807030600801618ISI: 000240352000008ScopusID: 2-s2.0-33747600159OAI: diva2:334019
QC 20100525Available from: 2010-08-05 Created: 2010-08-05Bibliographically approved

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