Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Synthesis of functionalized pyrrolidines by a highly stereoselective 3+2 -annulation reaction of N-tosyl-alpha-amino aldehydes and 1,3-bis(silyl)propenes
KTH, School of Chemical Science and Engineering (CHE), Chemistry, Organic Chemistry.
2007 (English)In: Synthesis (Stuttgart), ISSN 0039-7881, E-ISSN 1437-210X, no 10, 1576-1583 p.Article in journal (Refereed) Published
Abstract [en]

An efficient protocol for stereoselective construction of densely functionalized pyrrolidines by a [3+2]-annulation reaction of N-tosyl-alpha-amino aldehydes and 1,3-bis(silyl)propenes is described. This methodology is also applied as a key step in the synthesis of the polyhydroxylated pyrrolidine alkaloid 2,5-dideoxy-2,5-imino-D-glucitol (DGDP)

Place, publisher, year, edition, pages
2007. no 10, 1576-1583 p.
Keyword [en]
alpha-amino aldehyde, allylsilane, [3+2] annulation, pyrrolidine, alkaloid, 3+2 annulation, chlorosulfonyl isocyanate, tetrahydrofuran synthesis, substituted allylsilanes, pyrrolizidine alkaloids, asymmetric-synthesis, homoallylic amines, additions, silicon, vinylsilanes
Identifiers
URN: urn:nbn:se:kth:diva-16679DOI: 10.1055/s-2007-966046ISI: 000247095700025Scopus ID: 2-s2.0-34249800071OAI: oai:DiVA.org:kth-16679DiVA: diva2:334722
Note
QC 20100525Available from: 2010-08-05 Created: 2010-08-05 Last updated: 2017-12-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Somfai, Peter
By organisation
Organic Chemistry
In the same journal
Synthesis (Stuttgart)

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 23 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf