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Speckle tracking Echocardiography is a sensitive tool for the detection of myocardial ischemia: A pilot study from the catheterization laboratory during percutaneous coronary intervention
Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet.
2007 (English)In: Journal of the American Society of Echocardiography, ISSN 0894-7317, E-ISSN 1097-6795, Vol. 20, no 8, 974-981 p.Article in journal (Refereed) Published
Abstract [en]

Analysis of rotational myocardial motion has been reported to be a sensitive index of myocardial ischemia. In this study, circumferential and radial myocardial strain and displacement was monitored during angioplasty balloon-induced myocardial ischemia in 8 patients undergoing percutaneous coronary intervention. The circumferential and radial variables were measured simultaneously in parasternal short-axis view at the papillary muscle level using the recently introduced speckle tracking echocardiography technique that allows 2-dimensional, angle-independent, real-time evaluation of the myocardial motion (2-dimensional strain modality). Acute regional myocardial ischemia caused a significant reduction of circumferential (-35.6 +/- 23.1%) and radial (-27.1 +/- 23.2%) strain and displacement (-49.6 +/- 27.2% and -43.2 +/- 26.8%, respectively). Simultaneously, time to the respective peak systolic values became significantly prolonged, the circumferential ischemic response in temporal domain being more pronounced (P < .05). Speckle tracking echocardiography-based analysis of rotational myocardial motion has a potential to become an efficient clinical bedside tool in the detection of acute ischemic regional myocardial dysfunction.

Place, publisher, year, edition, pages
2007. Vol. 20, no 8, 974-981 p.
Keyword [en]
ventricular systolic function, canine left-ventricle, stress echocardiography, tissue doppler, dobutamine echocardiography, apex rotation, conscious dog, strain-rate, angioplasty, dysfunction
National Category
Medical and Health Sciences
URN: urn:nbn:se:kth:diva-16870DOI: 10.1016/j.echo.2007.01.029ISI: 000248728000011OAI: diva2:334913
QC 20100525Available from: 2010-08-05 Created: 2010-08-05 Last updated: 2012-03-23Bibliographically approved

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Brodin, Lars-Åke
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