Change search
ReferencesLink to record
Permanent link

Direct link
Resorbable Scaffolds from Three Different Techniques: Electrospun Fabrics, Salt-Leaching Porous Films, and Smooth Flat Surfaces
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology.ORCID iD: 0000-0002-1922-128X
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology.
Show others and affiliations
2008 (English)In: Macromolecular Bioscience, ISSN 1616-5187, E-ISSN 1616-5195, Vol. 8, no 10, 951-959 p.Article in journal (Refereed) Published
Abstract [en]

Nanofibrous scaffolds of poly[(L-lactide)-co-(1,5-dioxepan-2-one)] generated by electrospinning have been compared with porous films obtained by solvent cast/salt leaching and homogeneous films. A comparison between the fibrous materials and the homogeneous solvent-cast films revelead that the surface of the nanofibers was more hydrophobic and that the nanofibers were degraded more rapidly in the presence of proteinase. It was obvious that the strain-to-break was reduced by the nanofiber formation, it decreased from 370% to 130% independent of fiber diameter. These values were however considerably higher than the strain-to-break of the solvent-cast/salt leaching scaffold. In addition, the nanofibrous material accelerated the adhesion and growth of the mesenchymal stem cell compared to the smooth material.

Place, publisher, year, edition, pages
2008. Vol. 8, no 10, 951-959 p.
Keyword [en]
cell proliferation, degradation, electrospinning, structure/property, relations, tissue engineering, mechanical-properties, nanofiber scaffolds, fibers, cell, regeneration, membrane, adhesion
URN: urn:nbn:se:kth:diva-17925DOI: 10.1002/mabi.200700328ISI: 000260474100007ScopusID: 2-s2.0-60549094659OAI: diva2:335970
QC 20100525Available from: 2010-08-05 Created: 2010-08-05Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Finne Wistrand, AnnaAlbertsson, Ann-Christine
By organisation
Fibre and Polymer Technology
In the same journal
Macromolecular Bioscience

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 30 hits
ReferencesLink to record
Permanent link

Direct link