Evidence-Based Toxicology: "Sound Science" in New Disguise
2008 (English)In: International journal of occupational and environmental health, ISSN 1077-3525, Vol. 14, no 4, 299-306 p.Article in journal (Refereed) Published
The "evidence-based toxicology" proposed by Guzelian et al. departs radically from state-of-the-art toxicology by claiming that risks for humans can only be determined on the basis of human evidence. Just like the previous proposal of "sound science," "evidence-based toxicology" poses a heavy burden of proof on any effort to control exposures in order to reduce health risks to those exposed. The alleged connection between "evidence-based toxicology" and evidence-based medicine is misconceived, since the strict criteria for use of scientific data in evidence-based medicine concerns proof of therapeutic effects, while in "evidence-based toxicology" these criteria are applied to proof of harmful effects. The slogans "sound science" and "evidence-based toxicology" have both been put forward by persons with a history of extensive involvement with the tobacco industry.
Place, publisher, year, edition, pages
2008. Vol. 14, no 4, 299-306 p.
Evidence-based toxicology, evidence-based medicine, risk assessment, burden of proof, sound science, bias, Philip S. Guzelian, tobacco, Philip Morris, epidemiology faces, framework, causation, relevance, disease, humans, limits, risks
IdentifiersURN: urn:nbn:se:kth:diva-17993ISI: 000261076200008ScopusID: 2-s2.0-56549091509OAI: oai:DiVA.org:kth-17993DiVA: diva2:336038
QC 201005252010-08-052010-08-05Bibliographically approved