Systematic Comparison of HEA and HEMA as Initiators in Enzymatic Ring-Opening Polymerizations
2009 (English)In: Macromolecular Bioscience, ISSN 1616-5187, E-ISSN 1616-5195, Vol. 9, no 7, 713-720 p.Article in journal (Refereed) Published
Two initiators (HEA and HEMA) containing a cleavable ester bond were compared in the lipase-catalyzed ROP of CL and PDL. HEA and HEMA displayed similar reaction efficiencies as initiators (acyl acceptors) in the enzymatic ROP. However, transacylation reactions were found to be 15 times faster on the HEA-initiated polyesters as compared with the HEAAA initiated polyesters (HEA/HEMA moieties as acyl donors). While in both cases the amount of HEA- and HEMA-initiated polymers could be maximized by H short reaction times, a well-defined (meth)acrylation by this approach was not possible. Our results show that trans esterification reactions are present at high rates throughout the enzyme-catalyzed ROP.
Place, publisher, year, edition, pages
2009. Vol. 9, no 7, 713-720 p.
biocatalysis, enzymes, kinetics, polyesters, ring-opening polymerization, transfer radical polymerization, antarctica lipase-b, chemoenzymatic, synthesis, epsilon-caprolactone, graft-copolymers, polyesters, poly(epsilon-caprolactone), macromonomers, lactones, poly(omega-pentadecalactone)
IdentifiersURN: urn:nbn:se:kth:diva-18601DOI: 10.1002/mabi.200800290ISI: 000267962700011ScopusID: 2-s2.0-68649110083OAI: oai:DiVA.org:kth-18601DiVA: diva2:336648
QC 201005252010-08-052010-08-052011-01-26Bibliographically approved