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Complete separation of magnetic nanoparticles via chemical cleavage of dextran by ethylenediamine for intracellular uptake
KTH, School of Information and Communication Technology (ICT), Material Physics, Functional Materials, FNM.
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2010 (English)In: Journal of Materials Chemistry, ISSN 0959-9428, E-ISSN 1364-5501, Vol. 20, no 3, 444-447 p.Article in journal (Refereed) Published
Abstract [en]

Completely water dispersible and highly monodispersed superparamagnetic iron oxide nanoparticles (SPIONs) were prepared. The surface of SPIONs was modified with dual-crosslinked amine activated dextran (AMD) and chemical cleavage of AMD on SPIONs was carried out by ethylenediamine hydrochloride (EDA). Transmission electron microscopy (TEM) revealed that individual SPIONs were completely separated in water and the average diameter of resulting nanoparticles was 4.4 nm.

Place, publisher, year, edition, pages
2010. Vol. 20, no 3, 444-447 p.
Keyword [en]
iron-oxide nanoparticles, superparamagnetic nanoparticles, contrast, agents, nanocrystals, shell, particles, delivery, cancer, water
National Category
Materials Chemistry
URN: urn:nbn:se:kth:diva-19076DOI: 10.1039/b918416cISI: 000273038000005ScopusID: 2-s2.0-72949124387OAI: diva2:337123
QC 20100525Available from: 2010-08-05 Created: 2010-08-05 Last updated: 2011-01-25Bibliographically approved

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