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Highly Adhesive Phenolic Compounds as Interfacial Primers for Bone Fracture Fixations
KTH, School of Technology and Health (STH), Neuronic Engineering.
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology, Coating Technology.
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology, Coating Technology.
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology.ORCID iD: 0000-0002-9372-0829
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2010 (English)In: ACS APPLIED MATERIALS & INTERFACES, ISSN 1944-8244, Vol. 2, no 3, 654-657 p.Article in journal (Refereed) Published
Abstract [en]

Bone fractures are today scabilized with screws and metal plates. More complicated Fractures require alternative treatments that exclude harsh surgical conditions. By adapting the benign and UV initiated thiol-ene reaction, we efficiently fabricated triazine-based, fiber-reinforced adhesive patches within 2 s. To enhance their bone adhesion properties, we found that a pre-treatment step of bone surfaces with phenolic dopamine and poly(parahydroxystyrene) compounds was successful. The latter display the greatest E-module of 3.4 MPa in shear strength. All patches exhibited low cytotoxicity and can therefore find potential use in future treatments of bone fractures.

Place, publisher, year, edition, pages
2010. Vol. 2, no 3, 654-657 p.
Keyword [en]
bone, fracture, fibre, reinforced, adhesive, FRAP, thiol-ene, primer, DOPA, surface-chemistry, mytilus-edulis, proteins
National Category
Materials Engineering
Identifiers
URN: urn:nbn:se:kth:diva-19328DOI: 10.1021/am100002sISI: 000275825700012Scopus ID: 2-s2.0-77952295409OAI: oai:DiVA.org:kth-19328DiVA: diva2:337375
Funder
Swedish Research Council, 2006-3617
Note
QC 20110114Available from: 2010-08-05 Created: 2010-08-05 Last updated: 2011-01-14Bibliographically approved

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Hult, AndersMalkoch, Michael

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