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Solubility of paracetamol in binary and ternary mixtures of water plus acetone plus toluene
KTH, Superseded Departments, Chemical Engineering and Technology.
2000 (English)In: Journal of Chemical and Engineering Data, ISSN 0021-9568, E-ISSN 1520-5134, Vol. 45, no 3, 478-483 p.Article in journal (Refereed) Published
Abstract [en]

The solubility of paracetamol (4-hydroxyacetanilide) in binary mixtures of acetone + water and acetone + toluene and in ternary mixtures of water + acetone + toluene is reported. The temperature range is -5 to +30 degrees C. In acetone + water the solubility increases to a maximum at approximately 25 mass % water before decreasing to a much lower value in pure water as compared to pure acetone. In acetone + toluene the solubility decreases monotonically with increasing toluene concentration. The water content has a strong influence also in ternary mixtures. Activity coefficients in the saturated solutions are estimated.

Place, publisher, year, edition, pages
2000. Vol. 45, no 3, 478-483 p.
Keyword [en]
solvent mixtures, ethanol-water
URN: urn:nbn:se:kth:diva-19754ISI: 000087026800016OAI: diva2:338446
QC 20100525Available from: 2010-08-10 Created: 2010-08-10Bibliographically approved

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Rasmuson, Åke C.
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