Functional integration of adult-born neurons
2002 (English)In: Current Biology, ISSN 0960-9822, E-ISSN 1879-0445, Vol. 12, no 7, 606-608 p.Article in journal (Refereed) Published
Over the past decade, it has become clear that neural stem cells in the adult mammalian brain continuously generate new neurons, predominantly in the hippocampus and olfactory bulb . However, the central issue of whether these new neurons participate in functional synaptic circuitry has yet to be resolved. Here, we use virus-based transsynaptic neuronal tracing and c-Fos mapping of odor-induced neuronal activity to demonstrate that neurons generated in the adult functionally integrate into the synaptic circuitry of the brain.
Place, publisher, year, edition, pages
2002. Vol. 12, no 7, 606-608 p.
generated neurons, brain
IdentifiersURN: urn:nbn:se:kth:diva-21459ISI: 000174953600028OAI: oai:DiVA.org:kth-21459DiVA: diva2:340157
QC 201005252010-08-102010-08-10Bibliographically approved