Burst dynamics under mixed NMDA and AMPA drive in the models of the lamprey spinal CPG
2003 (English)In: Neurocomputing, ISSN 0925-2312, Vol. 52-54, 65-71 p.Article in journal (Refereed) Published
The spinal CPG of the lamprey is modeled using a chain of nonlinear oscillators. Each oscillator represents a small neuron population capable of bursting under mixed NMDA and AMPA drive. Parameters of the oscillator are derived from detailed conductance-based neuron models. Analysis and simulations of dynamics of a single oscillator, a chain of locally coupled excitatory oscillators and a chain of two pairs of excitatory and inhibitory oscillators in each segment are done. The roles of asymmetric couplings and additional rostral drive for generation of a traveling wave with one cycle per chain length in a realistic frequency range are studied.
Place, publisher, year, edition, pages
2003. Vol. 52-54, 65-71 p.
locomotiom, spinal cord, lamprey, modeling, intersegmental phase-lag, computer-simulations, neural networks, modulation, neurons
Bioinformatics (Computational Biology)
IdentifiersURN: urn:nbn:se:kth:diva-22589DOI: 10.1016/s0925-2312(02)00795-6ISI: 000183514300012OAI: oai:DiVA.org:kth-22589DiVA: diva2:341287
QC 20100525 QC 201112212010-08-102010-08-102011-12-21Bibliographically approved