Primary nucleation of vanillin explored by a novel multicell device
2003 (English)In: Industrial & Engineering Chemistry Research, ISSN 0888-5885, E-ISSN 1520-5045, Vol. 42, no 20, 4899-4909 p.Article in journal (Refereed) Published
A novel multicell apparatus is designed, constructed, and used to investigate crystal nucleation of vanillin in water/2-propanol solution (20 mass % of 2-propanol on a solute-free basis). The device contains 15 nucleation cells, with volumes of about 6 cm(3) each, in which the induction times for nucleation are measured simultaneously. The nucleation in the cells is continuously video-recorded and analyzed offline. The induction time for nucleation of vanillin is determined at various levels of supersaturation and temperature, and by classical nucleation theory the solid-liquid interfacial energy is estimated to 7.3 +/- 0.2 mJ m(-2). A large variation in the experimental data is observed, and this variation is analyzed by statistical methods.
Place, publisher, year, edition, pages
2003. Vol. 42, no 20, 4899-4909 p.
homogeneous nucleation, induction periods, kinetics, crystallization, crystals, growth, paracetamol, sulfate, time
IdentifiersURN: urn:nbn:se:kth:diva-22851DOI: 10.1021/ie0210412ISI: 000185616700045OAI: oai:DiVA.org:kth-22851DiVA: diva2:341549
QC 201005252010-08-102010-08-10Bibliographically approved