Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Pyridyl phosphinites and pyridyl phosphites from chiral pyridyl alcohols - A modular approach
KTH, Superseded Departments, Chemistry.
KTH, Superseded Departments, Chemistry.ORCID iD: 0000-0002-1743-7650
2003 (English)In: European Journal of Organic Chemistry, ISSN 1434-193X, E-ISSN 1099-0690, no 21, 4205-4215 p.Article in journal (Refereed) Published
Abstract [en]

Chiral arylated pyridyl alcohols, pyridyl phosphinites and pyridyl phosphites were prepared by Suzuki arylation and/or O-functionalization with a chlorodiarylphosphane or a chloro-diarylphosphite of chiral 2-bromo-6-(1-hydroxyalkyl)pyridines or 2-(1-hydroxyalkyl) pyridines, with the chirality originating from the chiral pool. The pyridyl alcohols were assessed as catalysts for the addition of diethylzinc to benzaldehyde and the P,N-ligands were employed in the palladium-catalysed substitutions of rac-1,3-diphenyl-2-propenyl acetate and rac-2-cyclohexenyl acetate with dimethyl malonate. Moderate enantioselectivities were observed in the catalytic reactions. We observed kinetic resolution of the racemic acetate when using one of the phosphite ligands. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).

Place, publisher, year, edition, pages
2003. no 21, 4205-4215 p.
Keyword [en]
asymmetric catalysis, chiral pool, palladium, pyridine ligands, zinc, enantioselective conjugate addition, asymmetric catalysis, allylic substitutions, enantiomeric excess, colorimetric assay, solid-phase, ligands, combinatorial, diethylzinc, discovery
Identifiers
URN: urn:nbn:se:kth:diva-22946DOI: 10.1002/ejoc.200300368ISI: 000186458000014OAI: oai:DiVA.org:kth-22946DiVA: diva2:341644
Note
QC 20100525Available from: 2010-08-10 Created: 2010-08-10 Last updated: 2017-12-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Moberg, Christina

Search in DiVA

By author/editor
Fischer, AndreasMoberg, Christina
By organisation
Chemistry
In the same journal
European Journal of Organic Chemistry

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 26 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf