Encapsulation of bovine serum albumin in temperature-programmed shell-in-shell structures
2003 (English)In: Macromolecular rapid communications, ISSN 1022-1336, E-ISSN 1521-3927, Vol. 24, no 16, 957-962 p.Article in journal (Refereed) Published
A novel approach to load a hydrophilic bovine serum albumin into drug carriers was proposed in terms of temperature-programmed shell-in-shell structures, which were fabricated with poly(N-isopropylacrlamide), poly(lactide), poly(ethylene glycol), and Au nanoparticles. Spherically well-defined shell-in-shell structures were constructed by a modified-double-emulsion method (MDEM). The lower critical solubility temperature of the structures was manipulated to 36.4degreesC which was confirmed by UV/Vis spectroscopy and DSC (Differential Scanning Calorimetry).
Place, publisher, year, edition, pages
2003. Vol. 24, no 16, 957-962 p.
block copolymers, drug delivery systems, poly(N-isopropylacrylamide), poly(lactide), self-assembly, drug-delivery, poly(n-isopropylacrylamide), nanoparticles, polymers, carriers
IdentifiersURN: urn:nbn:se:kth:diva-22960DOI: 10.1002/marc.200300059ISI: 000186573500007OAI: oai:DiVA.org:kth-22960DiVA: diva2:341658
QC 201005252010-08-102010-08-10Bibliographically approved