2004 (English)In: Electrophoresis, ISSN 0173-0835, E-ISSN 1522-2683, Vol. 25, no 9, 1280-1288 p.Article in journal (Refereed) Published
Protein-protein interactions play crucial roles in various biological pathways and functions. Therefore, the characterization of protein levels and also the network of interactions within an organism would contribute considerably to the understanding of life. The availability of the human genome sequence has created a range of new possibilities for biomedical research. A crucial challenge is to utilize the genetic information for better understanding of protein distribution and function in normal as well as in pathological biological processes. In this review, we have focused on different platforms used for systematic genome-based proteome analyses. These technologies are in many ways complementary and should be seen as various ways to elucidate different functions of the proteome.
Place, publisher, year, edition, pages
2004. Vol. 25, no 9, 1280-1288 p.
genomics, protein interactions, protein localization, protein modifications, proteomics, review, protein-protein interactions, saccharomyces-cerevisiae, structural genomics, mass-spectrometry, subcellular-localization, global analysis, genetic system, yeast proteome, beta-lactamase, in-vivo
IdentifiersURN: urn:nbn:se:kth:diva-23463DOI: 10.1002/elps.200405846ISI: 000221735100015ScopusID: 2-s2.0-3042628524OAI: oai:DiVA.org:kth-23463DiVA: diva2:342161
QC 20100525 QC 201110202010-08-102010-08-102011-10-20Bibliographically approved