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Study of interaction between red-tide toxin, domoic acid and double-stranded DNA by capillary zone electrophoresis
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2004 (English)In: Chinese Chemical Letters, ISSN 1001-8417, E-ISSN 1878-5964, Vol. 15, no 9, 1079-1082 p.Article in journal (Refereed) Published
Abstract [en]

The interactions between amnesic red-tide toxin, domoic acid (DA) and 14mer double-stranded DNA (dsDNA with three kinds of sequences) were studied by capillary zone electrophoresis (CZE). For the dsDNA with a sequence of 5'-CCCCCTATACCCGC-3', the amount of free dsDNA decreases with the increase of added DA; and the signal of DA-dsDNA complex was observed. Meanwhile, the other two dsDNAs, 5'-(C)12GC-3' and 5'-(AT)7-3', the existence of DA could not lead to the change of dsDNA signal and indicated that there is no interaction between DA and these two dsDNAs.

Place, publisher, year, edition, pages
2004. Vol. 15, no 9, 1079-1082 p.
Keyword [en]
DA, dsDNA, interaction, capillary zone electrophoresis
Identifiers
URN: urn:nbn:se:kth:diva-23723ISI: 000223852800021OAI: oai:DiVA.org:kth-23723DiVA: diva2:342422
Note
QC 20100525Available from: 2010-08-10 Created: 2010-08-10 Last updated: 2017-12-12Bibliographically approved

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Sun, Licheng

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