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Nanoliter liquid handling on a low cost disposable with embedded fluid actuators
KTH, School of Electrical Engineering (EES), Microsystem Technology.
KTH, School of Electrical Engineering (EES), Microsystem Technology.
KTH, School of Electrical Engineering (EES), Microsystem Technology.
KTH, School of Electrical Engineering (EES), Microsystem Technology.
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2005 (English)In: Transducers '05, Digest of Technical Papers, Vols 1 and 2: Digest of Technical Papers, Vols 1 and 2, NEW YORK: IEEE , 2005, 356-359 p.Conference paper, Published paper (Refereed)
Abstract [en]

In this work we present the development of a disposable liquid handling lab-on-a-chip (LOC) system with embedded actuators for applications in analytical chemistry. The proposed nanoliter liquid handling is based on a temperature sensitive silicone elastomer composite, consisting of PDMS and expandable microspheres. In our LOC system, we integrate active dosing, transportation and merging of nanoliter liquid volumes. The disposable successfully demonstrates precise sample volume control with smart microfluidic manipulation and on-chip active microfluidic components. It is entirely fabricated from low-cost materials using wafer-level processing. Moreover, a biochemical luminescent reaction was successfully conducted to exemplify its applicability as an LOC.

Place, publisher, year, edition, pages
NEW YORK: IEEE , 2005. 356-359 p.
Keyword [en]
microfluidics, lab-on-a-chip, disposable
National Category
Electrical Engineering, Electronic Engineering, Information Engineering
Identifiers
URN: urn:nbn:se:kth:diva-24787ISI: 000232189100086Scopus ID: 2-s2.0-27544440954OAI: oai:DiVA.org:kth-24787DiVA: diva2:355010
Conference
13th International Conference on Solid-State Sensors, Actuators and Microsystems Seoul, SOUTH KOREA, JUN 05-09, 2005
Note
QC 20101005Available from: 2010-10-05 Created: 2010-09-27 Last updated: 2012-03-21Bibliographically approved

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Stemme, Göran

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