Nanoliter liquid handling on a low cost disposable with embedded fluid actuators
2005 (English)In: Transducers '05, Digest of Technical Papers, Vols 1 and 2: Digest of Technical Papers, Vols 1 and 2, NEW YORK: IEEE , 2005, 356-359 p.Conference paper (Refereed)
In this work we present the development of a disposable liquid handling lab-on-a-chip (LOC) system with embedded actuators for applications in analytical chemistry. The proposed nanoliter liquid handling is based on a temperature sensitive silicone elastomer composite, consisting of PDMS and expandable microspheres. In our LOC system, we integrate active dosing, transportation and merging of nanoliter liquid volumes. The disposable successfully demonstrates precise sample volume control with smart microfluidic manipulation and on-chip active microfluidic components. It is entirely fabricated from low-cost materials using wafer-level processing. Moreover, a biochemical luminescent reaction was successfully conducted to exemplify its applicability as an LOC.
Place, publisher, year, edition, pages
NEW YORK: IEEE , 2005. 356-359 p.
microfluidics, lab-on-a-chip, disposable
Electrical Engineering, Electronic Engineering, Information Engineering
IdentifiersURN: urn:nbn:se:kth:diva-24787ISI: 000232189100086ScopusID: 2-s2.0-27544440954OAI: oai:DiVA.org:kth-24787DiVA: diva2:355010
13th International Conference on Solid-State Sensors, Actuators and Microsystems Seoul, SOUTH KOREA, JUN 05-09, 2005
QC 201010052010-10-052010-09-272012-03-21Bibliographically approved