Change search
ReferencesLink to record
Permanent link

Direct link
A constitutive model for smooth muscle including active tone and passive viscoelastic behaviour
KTH, School of Engineering Sciences (SCI), Solid Mechanics (Dept.).
2010 (English)In: Mathematical Medicine and Biology, ISSN 1477-8599, E-ISSN 1477-8602, Vol. 27, no 2, 129-155 p.Article in journal (Refereed) Published
Abstract [en]

A new constitutive model for the biomechanical behaviour of smooth muscle tissue is proposed. The active muscle contraction is accomplished by the relative sliding between actin and myosin filaments, comprising contractile units in the smooth muscle cells. The model includes a chemical part, governing the cross-bridge (myosin head) cycling, that is responsible for the filament sliding. The number of activated cross-bridges govern the contractile force generated and also the contraction speed. A strain-energy function is used to describe the mechanical behaviour of the smooth muscle tissue. Besides the active contractile apparatus, the mechanical model also incorporates a passive viscoelastic part. The constitutive model was calibrated with respect to experiments on smooth muscle tissue from swine carotid artery and guinea pig taenia coli, in terms of isometric and isotonic tensile test results. The model was fully able to reproduce the experimental results.

Place, publisher, year, edition, pages
2010. Vol. 27, no 2, 129-155 p.
Keyword [en]
biomechanics, smooth muscle, constitutive model, viscoelasticity
National Category
Applied Mechanics
URN: urn:nbn:se:kth:diva-27536DOI: 10.1093/imammb/dqp017ISI: 000278438800002ScopusID: 2-s2.0-77955670405OAI: diva2:379239
QC 20101217Available from: 2010-12-17 Created: 2010-12-13 Last updated: 2010-12-17Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Kroon, Martin
By organisation
Solid Mechanics (Dept.)
In the same journal
Mathematical Medicine and Biology
Applied Mechanics

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 34 hits
ReferencesLink to record
Permanent link

Direct link