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Mutated variant of Candida antarctica lipase B in (S)-selective dynamic kinetic resolution of secondary alcohols
Stockholm Univ, Arrhenius Lab, Dept Organ Chem.
KTH, School of Biotechnology (BIO), Biochemistry.
KTH, School of Biotechnology (BIO), Biochemistry.ORCID iD: 0000-0002-4066-2776
KTH, School of Biotechnology (BIO), Biochemistry.
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2011 (English)In: Organic and biomolecular chemistry, ISSN 1477-0520, E-ISSN 1477-0539, Vol. 9, no 1, 81-82 p.Article in journal (Refereed) Published
Abstract [en]

An (S)-selective dynamic kinetic resolution of secondary alcohols, employing a mutated variant of Candida antarctica lipase B (CalB) gave products in 84-88% yield and in 90-97% ee.

Place, publisher, year, edition, pages
2011. Vol. 9, no 1, 81-82 p.
Keyword [en]
Candida antarctica lipase B, Dynamic kinetic resolution, Secondary alcohols, Isomers
National Category
Biochemistry and Molecular Biology
Identifiers
URN: urn:nbn:se:kth:diva-28182DOI: 10.1039/c0ob00748jISI: 000285157600011OAI: oai:DiVA.org:kth-28182DiVA: diva2:385179
Funder
Swedish Research CouncilKnut and Alice Wallenberg Foundation
Note
QC 20110111Available from: 2011-01-11 Created: 2011-01-10 Last updated: 2017-12-11Bibliographically approved

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Syrén, Per-Olof

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