Feasibility Study for Photon Counting Detector for High Resolution Pre Clinical SPECT
2009 (English)In: 2008 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (2008 NSS/MIC), 2009, 3975-3979 p.Conference paper (Refereed)
We plan to integrate a photon counting, large area, high spatial resolution, high efficiency detector in a system for pre-clinical SPECT. We are aiming for a high spatial resolution for the detector of around 20 mu m. The agent for radiolabelling is assumed to be I-125, with an emission peak at 27 keV, since it is readily available. The aim of this feasibility study was to optimize the scintillator and electronics. We consider a complementary metal-oxide-semiconductor (CMOS) circuit together with a columnar CsI scintillator. In our case CMOS is advantageous over CCD due to a more flexible readout and an opportunity for data processing and trigger logic at the pixel level. The position of the x-ray interaction in the scintillator can be estimated with high accuracy by fitting a two-dimensional Gaussian curve to the pixel hit-map. The goal of this study is to determine optimal scintillator thickness, pixel size, readout rate and the corresponding achievable spatial resolution. Results for a CA thickness of 600 mu m show a detection efficiency close to 90 % and a spatial resolution in the range of 20 mu m. Optimum pixel size for this application is between 40 - 60 mu m and as long as the readout speed exceeds 750 Hz the noise from the dark current will not be significant.
Place, publisher, year, edition, pages
2009. 3975-3979 p.
, IEEE NUCLEAR SCIENCE SYMPOSIUM - CONFERENCE RECORD, ISSN 1082-3654
Complementary metal oxide semiconductors, Detection efficiency, Emission peaks, Feasibility studies, Gaussian curves, High efficiency, High resolution, High spatial resolution, Photon counting, Photon counting detectors, Pixel level, Pixel size, Pre-clinical, Radiolabelling, Readout rate, Spatial resolution, X-ray interaction, Charge coupled devices, Curve fitting, Data processing, Decision making, Detectors, Image resolution, Luminescence, Photons, Planning, Resource allocation, Scintillation, Scintillation counters
Radiology, Nuclear Medicine and Medical Imaging
IdentifiersURN: urn:nbn:se:kth:diva-30734DOI: 10.1109/NSSMIC.2008.4774154ISI: 000268656001281ScopusID: 2-s2.0-67649196785ISBN: 978-1-4244-2714-7OAI: oai:DiVA.org:kth-30734DiVA: diva2:401991
IEEE Nuclear Science Symposium/Medical Imaging Conference, Dresden, GERMANY, OCT 19-25, 2008
QC 201103042011-03-042011-03-042013-12-18Bibliographically approved