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Feasibility Study for Photon Counting Detector for High Resolution Pre Clinical SPECT
KTH, School of Engineering Sciences (SCI), Physics, Physics of Medical Imaging.
KTH, School of Engineering Sciences (SCI), Physics, Physics of Medical Imaging.ORCID iD: 0000-0002-3039-9791
2009 (English)In: 2008 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (2008 NSS/MIC), 2009, 3975-3979 p.Conference paper, Published paper (Refereed)
Abstract [en]

We plan to integrate a photon counting, large area, high spatial resolution, high efficiency detector in a system for pre-clinical SPECT. We are aiming for a high spatial resolution for the detector of around 20 mu m. The agent for radiolabelling is assumed to be I-125, with an emission peak at 27 keV, since it is readily available. The aim of this feasibility study was to optimize the scintillator and electronics. We consider a complementary metal-oxide-semiconductor (CMOS) circuit together with a columnar CsI scintillator. In our case CMOS is advantageous over CCD due to a more flexible readout and an opportunity for data processing and trigger logic at the pixel level. The position of the x-ray interaction in the scintillator can be estimated with high accuracy by fitting a two-dimensional Gaussian curve to the pixel hit-map. The goal of this study is to determine optimal scintillator thickness, pixel size, readout rate and the corresponding achievable spatial resolution. Results for a CA thickness of 600 mu m show a detection efficiency close to 90 % and a spatial resolution in the range of 20 mu m. Optimum pixel size for this application is between 40 - 60 mu m and as long as the readout speed exceeds 750 Hz the noise from the dark current will not be significant.

Place, publisher, year, edition, pages
2009. 3975-3979 p.
Series
IEEE NUCLEAR SCIENCE SYMPOSIUM - CONFERENCE RECORD, ISSN 1082-3654
Keyword [en]
Complementary metal oxide semiconductors, Detection efficiency, Emission peaks, Feasibility studies, Gaussian curves, High efficiency, High resolution, High spatial resolution, Photon counting, Photon counting detectors, Pixel level, Pixel size, Pre-clinical, Radiolabelling, Readout rate, Spatial resolution, X-ray interaction, Charge coupled devices, Curve fitting, Data processing, Decision making, Detectors, Image resolution, Luminescence, Photons, Planning, Resource allocation, Scintillation, Scintillation counters
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:kth:diva-30734DOI: 10.1109/NSSMIC.2008.4774154ISI: 000268656001281Scopus ID: 2-s2.0-67649196785ISBN: 978-1-4244-2714-7 (print)OAI: oai:DiVA.org:kth-30734DiVA: diva2:401991
Conference
IEEE Nuclear Science Symposium/Medical Imaging Conference, Dresden, GERMANY, OCT 19-25, 2008
Note

QC 20110304

Available from: 2011-03-04 Created: 2011-03-04 Last updated: 2013-12-18Bibliographically approved
In thesis
1. HyperSPECT: a new instrument for high resolution single photon emission computed tomography
Open this publication in new window or tab >>HyperSPECT: a new instrument for high resolution single photon emission computed tomography
2013 (English)Licentiate thesis, comprehensive summary (Other academic)
Place, publisher, year, edition, pages
Stockholm: KTH Royal Institute of Technology, 2013. vi, 24 p.
Series
Trita-FYS, ISSN 0280-316X ; 2013:63
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
urn:nbn:se:kth:diva-138301 (URN)978-91-7501-946-8 (ISBN)
Presentation
2013-12-13, Sal A2:1003, AlbaNova Universitetcentrum, Roslagstullsbacken 21, Stockholm, 13:00
Opponent
Supervisors
Note

QC 20131218

Available from: 2013-12-18 Created: 2013-12-18Bibliographically approved

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