Synthesis of New Chiral Schiff Bases Containing Bromo- and Iodo-Functionalized Hydroxynaphthalene Frameworks
2011 (English)In: Synthetic Communications, ISSN 0039-7911, E-ISSN 1532-2432, Vol. 41, no 9, 1381-1393 p.Article in journal (Refereed) Published
[image omitted] Two series of chiral Schiff bases 3a-g and 4a-g containing bromo- and iodo-functionalized hydroxynaphthalene frameworks were conveniently prepared in acceptable to moderate yields by controlled halogenation of hydroxynaphthaldehyde and then condensation of the corresponding mono-, di-, and trihalohydroxynaphthaldehyde with the chiral amino alcohol. Except for 4d, the Schiff bases 3a-g, 4a-c, and 4e-g prepared in the present work have not been reported in literature so far, and they might be used as effective chiral inducers in some asymmetrically synthetic reactions.
Place, publisher, year, edition, pages
2011. Vol. 41, no 9, 1381-1393 p.
Chiral schiff base, condensation, controlled halogenation, halohydroxynaphthaldehyde
IdentifiersURN: urn:nbn:se:kth:diva-32590DOI: 10.1080/00397911.2010.486505ISI: 000288950300015ScopusID: 2-s2.0-79953661193OAI: oai:DiVA.org:kth-32590DiVA: diva2:412182
FunderKnut and Alice Wallenberg Foundation
QC 201104212011-04-212011-04-182011-04-21Bibliographically approved