Neural Signal Transmission Measurements with a Conductive Polymer Microelectrode Array
2011 (English)In: Electrical engineering in Japan (Print), ISSN 0424-7760, E-ISSN 1520-6416, Vol. 177, no 1, 37-42 p.Article in journal (Refereed) Published
The neural activity of dissociated cultures of mouse cortical neurons was measured with a conductive polymer microelectrode array. Each electrode was electrochemically polymerized from (3,4-ethylenedioxythiophene)-poly(styrenesulfonate) and ethylenedioxythiophene on indium tin oxide electrodes. The spike activity of the cortical neurons was measured with the conducting polymer MEA and spike train cross-correlograms were calculated to predict the type of synaptic connection. Both excitatory and inhibitory synaptic connections were identified after 6 to 8 days in vitro. These results show that it is possible to determine the interaction between excitatory and inhibitory neurons in relation to information processing with this new polymer electrode.
Place, publisher, year, edition, pages
2011. Vol. 177, no 1, 37-42 p.
conductive polymer, microelectrode array, neural network; spike, synaptic connection
Electrical Engineering, Electronic Engineering, Information Engineering
IdentifiersURN: urn:nbn:se:kth:diva-36251DOI: 10.1002/eej.21155ISI: 000292028800006ScopusID: 2-s2.0-79959423051OAI: oai:DiVA.org:kth-36251DiVA: diva2:430492
QC 201107112011-07-112011-07-112011-07-11Bibliographically approved