Synthesis of 3-aryl-5-t-butylsalicylaldehydes and their chiral Schiff base compounds
2007 (English)In: Synthetic Communications, ISSN 0039-7911, E-ISSN 1532-2432, Vol. 37, no 19-21, 3815-3826 p.Article in journal (Refereed) Published
Six meta-substituted salicylaldehyde compounds have been prepared in 68-90% yields by the Suzuki-Miyaura coupling reaction using 3-bromo-5-t-butylsalicylaldehyde (la) and arylboronic acids (2a-f) as reactants. Among the obtained products, 3-(4-fluorophenyl)-5-t-butylsalicylaldehyde (3b), 3-(4-methylphenyl)-5-t-butylsalicylaldehyde (3d), 3-(1-naphthyl)-5-t-butylsalicylaldehyde (3e), and 3-(2-naphthyl)-5-t-butylsalicylaldehyde (3f) have not been reported so far. A series of new Schiff base ligands (L1-L10) were obtained in 51-89% yields from these salicylaldehyde derivatives.
Place, publisher, year, edition, pages
2007. Vol. 37, no 19-21, 3815-3826 p.
3-bromo-5-t-butylsafcylaldehyde, chiral Schiff base ligands, meta-substituted, salicylaldehyde, Suzulu-Miyaura coupling reaction
IdentifiersURN: urn:nbn:se:kth:diva-37066DOI: 10.1080/00397910701572423ISI: 000250737500056ScopusID: 2-s2.0-35348976022OAI: oai:DiVA.org:kth-37066DiVA: diva2:431948