A Suzuki-type cross-coupling reaction of arylacetylene halides with arylboronic acids
2011 (English)In: Applied organometallic chemistry, ISSN 0268-2605, E-ISSN 1099-0739, Vol. 25, no 7, 514-520 p.Article in journal (Refereed) Published
A PdCl(2)-catalyzed direct alkynylation of arylboronic acids to give diarylacetylenes is described. The optimal conditions using PdCl(2) as catalyst, MeOH-PhMe-H(2)O as solvent and K(2)CO(3) as base effectively suppressed the formation of homo-coupling product and afforded moderate to good yield of the desired unsymmetrical coupling product. This reaction represents a Suzuki-type sp(2)(C-B)-sp(C-X) cross-coupling.
Place, publisher, year, edition, pages
2011. Vol. 25, no 7, 514-520 p.
Suzuki cross-coupling, diarylacetylene, palladium chloride, alkynylation
IdentifiersURN: urn:nbn:se:kth:diva-37164DOI: 10.1002/aoc.1795ISI: 000292710400006ScopusID: 2-s2.0-79959700466OAI: oai:DiVA.org:kth-37164DiVA: diva2:432321