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Facile polyester surface functionalization via hydrolysis and cell-recognizing peptide attachment
KTH, School of Chemical Science and Engineering (CHE).
KTH, School of Chemical Science and Engineering (CHE).
2006 (English)In: Polymer international, ISSN 0959-8103, E-ISSN 1097-0126, Vol. 55, no 11, 1336-1340 p.Article in journal (Refereed) Published
Abstract [en]

Facile surface modification of biodegradable polycaprolactone via alkali hydrolysis and subsequent attachment of a cell-recognizing peptide to the hydrolysed polymer surface is reported. Surface hydrolysis was carried out in sodium hydroxide solution. The modification was studied with regard to hydrolysis time, temperature and alkaline concentration. A cell-recognizing peptide was covalently attached to the hydrolysed polymer surface. Contact angle measurements, X-ray photoelectron spectroscopy and ultraviolet spectroscopy were used to characterize the modified surface and to confirm the occurrence of the coupling reaction.

Place, publisher, year, edition, pages
2006. Vol. 55, no 11, 1336-1340 p.
Keyword [en]
biomaterials, functionalization of polymers, hydrolysis, peptide coupling
National Category
Chemical Sciences
URN: urn:nbn:se:kth:diva-37652DOI: 10.1002/pi.2090ISI: 000241203400020ScopusID: 2-s2.0-33750112282OAI: diva2:434651
Available from: 2011-08-16 Created: 2011-08-16 Last updated: 2011-08-16Bibliographically approved

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Sun, HuiÖnneby, Sara
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