Biosticker: patterned microfluidic stickers for rapid integration with microarrays
2011 (English)In: The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS 2011), Chemical and Biological Microsystems Society , 2011, 311-313 p.Conference paper (Refereed)
We present a one-step, reversible, and biocompatible bonding method of a stiff patterned microfluidic "Biosticker", based on off-stoichiometry thiol-ene (OSTE) polymers , to state-of-the-art spotted microarray surfaces. The method aims at improving and simplifying the batch back-end processing of microarrays. We illustrate its ease of use in two applications: a high sensitivity flow-through protein assay; and a DNA-hybridization test. Read-out was performed in a standard highvolume array scanner, and showed excellent spot homogeneity and intensity. The Biosticker is aimed to be a plug-in for existing microarray platforms to enable faster protein assays and DNA hybridizations through mass transport optimization.
Place, publisher, year, edition, pages
Chemical and Biological Microsystems Society , 2011. 311-313 p.
microarrays, lab-on-chip loc, OSTE, off-stoichiometry thiol-ene, microfluidic packaging
Electrical Engineering, Electronic Engineering, Information Engineering
IdentifiersURN: urn:nbn:se:kth:diva-38609ScopusID: 2-s2.0-84877953846ISBN: 9781618395955OAI: oai:DiVA.org:kth-38609DiVA: diva2:437756
The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS 2011)
QC 201109022011-08-302011-08-302015-06-03Bibliographically approved