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Physical and numerical modeling of dissection propagation in arteries caused by balloon angioplasty
KTH, School of Engineering Sciences (SCI), Solid Mechanics (Dept.).
KTH, School of Engineering Sciences (SCI), Solid Mechanics (Dept.).
2005 (English)In: Proceedings of the Third IASTED International Conference on BIOMECHANICS / [ed] Hamza, MH, 2005, 229-233 p.Conference paper (Refereed)
Abstract [en]

Arterial dissections Caused by balloon angioplasty has been implicated as a contributing factor to both acute procedural complications and chronic restenosis of the treatment site. However, no related biomechanical studies are known in the literature. The mechanical properties of the arterial wall are controlled by the rubber-like protein elastin, fibrous protein collagen and smooth muscle cells. In the media of elastic arteries these constituents are found in thin layers that are arranged in repeating lamellar units and favor dissection type of failure. The presented approach models the dissection of the media by means of strong discontinuities and the application of the theory of cohesive zones. Thereby, the dissection is regarded as a gradual process in which separation between incipient material surfaces is resisted by cohesive traction. The applied numerical frame is based on the Partition of Unity Finite Element Method (PUFEM) and has been utilized for tetrahedral elements. A tracking algorithm for 3D non-planar cracks captures the evolution of multiple non-interacting dissections. The proposed concept is applied to investigate the dissection of the media due to balloon angioplasty, where the associated material parameters are determined from failure experiments on human tissue.

Place, publisher, year, edition, pages
2005. 229-233 p.
Keyword [en]
artery, media, dissection, balloon angioplasty, PUFEM
National Category
URN: urn:nbn:se:kth:diva-43329ISI: 000232755400043ISBN: 0-88986-532-9OAI: diva2:448430
3rd IASTED International Conference on Biomechanics Location: Benidorm, SPAIN Date: SEP 07-09, 2005
QC 20111017Available from: 2011-10-17 Created: 2011-10-14 Last updated: 2011-10-17Bibliographically approved

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Gasser, T. ChristianHolzapfel, Gerhard A.
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Solid Mechanics (Dept.)

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