Change search
ReferencesLink to record
Permanent link

Direct link
mGluR-mediated calcium oscillations in the lamprey: a computational model
KTH, Superseded Departments, Numerical Analysis and Computer Science, NADA.
Show others and affiliations
2004 (English)In: COMPUTATIONAL NEUROSCIENCE: TRENDS IN RESEARCH 2004, AMSTERDAM: ELSEVIER SCIENCE BV , 2004, 431-435 p.Conference paper (Refereed)
Abstract [en]

Slow Ca2(+) oscillations caused by release from intracellular stores have been observed in neurons in the lamprey spinal cord. These oscillations are triggered by activation of metabotropic glutamate receptors on the cell surface. The pathway leading from receptor activation to the inositol triphosphate-mediated release of Ca2(+) from the endoplasmatic reticulum has been modelled in order to facilitate further understanding of the nature of these oscillations. The model generates Ca2(+) oscillations with a frequency range of 0.01-0.09 Hz. A prediction of the model is that the frequency will increase with a stronger extracellular glutamate signal.

Place, publisher, year, edition, pages
Keyword [en]
mGluR5, calcium oscillations, lamprey, spinal cord
National Category
Computer Science
URN: urn:nbn:se:kth:diva-44003DOI: 10.1016/j.neucom.2004.02.077ISI: 000223887200064ISBN: 0-444-51649-2OAI: diva2:449100
12th Annual Computational Neuroscience Meeting (CNS 03). Alicante, SPAIN. JUL 05-09, 2003
QC 20111019Available from: 2011-10-19 Created: 2011-10-19 Last updated: 2011-10-19Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Huss, MikaelKotaleski, Jeanette Hällgren
By organisation
Numerical Analysis and Computer Science, NADA
Computer Science

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 28 hits
ReferencesLink to record
Permanent link

Direct link