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The effect of breathing hyperoxic gas during simulated submarine escape on venous gas emboli and decompression illness
Swedish Defence Research Agency.
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2003 (English)In: Undersea & Hyperbaric Medicine, ISSN 1066-2936, Vol. 30, no 3, 163-174 p.Article in journal (Refereed) Published
Abstract [en]

Raised internal pressure in a distressed submarine rapidly increases the risk of decompression sickness (DCS) following submarine escape. The hypothesis that breathing a hyperoxic gas during escape may reduce the risk of DCS was tested using goats. Shallow air saturation and simulated submarine escape dives were carried out either singularly or in combination (saturation, escape, or saturation followed by escape) using air or 60% / 40% oxygen (O2) / nitrogen (N2) mixture as breathing gas during the escapes. Post-surfacing, animals were observed for signs of DCI and O2 toxicity. Precordial Doppler ultrasound was used to score venous gas emboli (VGE) using the Kisman Masurel (KM) scale. Following escape from 2.5 MPa, the rate at which VGE disappeared in the hyperoxic group (n = 8) was significantly faster(p < 0.05) than the air group (n = 7). One case of pulmonary barotrauma with arterial gas embolism occurred in the air group, but no cases of DCS were observed. After saturation at 0.18 MPa followed by escape from 2.5 MPa, DCS occurred in four of 15 animals in the air group and in two of 16 animals in the hyperoxic group. The rate of disappearance of VGE was significantly faster (p < 0.01) in the hyperoxic group. O2 toxicity was not discernible in any of the animals.

Place, publisher, year, edition, pages
2003. Vol. 30, no 3, 163-174 p.
Keyword [en]
decompression illness, submarine escape, hyperoxia, oxygen toxicity, saturation, venous gas emboli
National Category
Physiology
Identifiers
URN: urn:nbn:se:kth:diva-45334ISI: 000186150300001PubMedID: 14620096OAI: oai:DiVA.org:kth-45334DiVA: diva2:452348
Note
QC 20111102Available from: 2011-10-28 Created: 2011-10-28 Last updated: 2018-01-12Bibliographically approved

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CiteExportLink to record
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  • apa
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