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Effects of dietary lipids on frequency and force in atrial muscle at 10 MPa
Swedish Defence Research Agency.
1987 (English)In: Undersea biomedical research, ISSN 0093-5387, Vol. 14, no 1, 31-43 p.Article in journal (Refereed) Published
Abstract [en]

Spontaneously beating atrial preparations, from rats fed different lipid diets, were compressed to 10 MPa. The following observations were made: Different lipid diets altered the ratio of omega-6/omega-3 polyunsaturated fatty acids of the cardiac phospholipids. Beating frequency and twitch tension at surface pressure was unaffected by the diets. Compression to 10 MPa caused a decrease in spontaneous beating frequency and an increased twitch tension in all preparations. The decrease in beating frequency was inversely related to the omega-6/omega-3 ratio. Pressure induced increase in twitch tension was not affected by the diets. N2O dissolved in the tissue bath solution partly counteracted the pressure-induced changes.

Place, publisher, year, edition, pages
1987. Vol. 14, no 1, 31-43 p.
National Category
URN: urn:nbn:se:kth:diva-45344ISI: A1987F615000004PubMedID: 3810991OAI: diva2:452365
QC 20111102Available from: 2011-10-28 Created: 2011-10-28 Last updated: 2011-11-02Bibliographically approved

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Gennser, Mikael

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