Effects of dietary lipids on frequency and force in atrial muscle at 10 MPa
1987 (English)In: Undersea biomedical research, ISSN 0093-5387, Vol. 14, no 1, 31-43 p.Article in journal (Refereed) Published
Spontaneously beating atrial preparations, from rats fed different lipid diets, were compressed to 10 MPa. The following observations were made: Different lipid diets altered the ratio of omega-6/omega-3 polyunsaturated fatty acids of the cardiac phospholipids. Beating frequency and twitch tension at surface pressure was unaffected by the diets. Compression to 10 MPa caused a decrease in spontaneous beating frequency and an increased twitch tension in all preparations. The decrease in beating frequency was inversely related to the omega-6/omega-3 ratio. Pressure induced increase in twitch tension was not affected by the diets. N2O dissolved in the tissue bath solution partly counteracted the pressure-induced changes.
Place, publisher, year, edition, pages
1987. Vol. 14, no 1, 31-43 p.
IdentifiersURN: urn:nbn:se:kth:diva-45344ISI: A1987F615000004PubMedID: 3810991OAI: oai:DiVA.org:kth-45344DiVA: diva2:452365
QC 201111022011-10-282011-10-282011-11-02Bibliographically approved