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Enhancing the utility of ProstaScint SPECT scans for patient management
New York University, Department of Radiology. (Nuclear Medicine)
New York University.
New York University.
KTH, School of Information and Communication Technology (ICT), Communication Systems, CoS. (Computer Communications)ORCID iD: 0000-0002-6066-746X
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2006 (English)In: Journal of medical systems, ISSN 0148-5598, E-ISSN 1573-689X, Vol. 30, no 2, 123-132 p.Article in journal (Refereed) Published
Abstract [en]

This project investigated reducing the artifact content of In-111 ProstaScint SPECT scans for use in treatment planning and management. Forty-one patients who had undergone CT or MRI scans and simultaneous Tc-99m RBC/In-111 ProstaScint SPECT scans were included. SPECT volume sets, reconstructed using Ordered Set-Expectation Maximum (OS-EM) were compared against those reconstructed with standard Filtered Back projection (FBP). Bladder activity in Tc-99m scans was suppressed within an ellipsoidal volume. Tc-99m voxel values were subtracted from the corresponding In-111 after scaling based on peak activity within the descending aorta. The SPECT volume data sets were merged with the CT or MRI scans before and after processing. Volume merging, based both on visual assessment and statistical evaluation, was not affected. Thus iterative reconstruction together with bladder suppression and blood pool subtraction may improve the interpretation and utility of ProstaScint SPECT scans for patient management.

Place, publisher, year, edition, pages
Springer-Verlag New York, 2006. Vol. 30, no 2, 123-132 p.
Keyword [en]
Aged Aged, 80 and over Humans Male Middle Aged Patient Care Prostatic Neoplasms Retrospective Studies Tomography, Emission-Computed, Single-Photon
National Category
Radiology, Nuclear Medicine and Medical Imaging
Research subject
URN: urn:nbn:se:kth:diva-46752DOI: 10.1007/s10916-005-7987-yPubMedID: 16705997OAI: diva2:454133
QC 20111107Available from: 2011-11-05 Created: 2011-11-05 Last updated: 2013-09-09Bibliographically approved

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Maguire Jr., Gerald Q.
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