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A versatile functional-anatomic image fusion method for volume data sets
New York University.
KTH, Superseded Departments, Teleinformatics. (Computer Communications)ORCID iD: 0000-0002-6066-746X
New York University.
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2001 (English)In: Journal of medical systems, ISSN 0148-5598, E-ISSN 1573-689X, Vol. 25, no 5, 297-307 p.Article in journal (Refereed) Published
Abstract [en]

We describe and validate a volumetric three-dimensional registration method, and compare it to our previously validated two-dimensional/three-dimensional method. {CT/MRI} and {SPECT} data from 14 patients were interactively fused using a polynomial warping technique. Registration accuracy was confirmed visually and by a nonsignificant F value from multivariate analysis of the transformed landmarks, a significant difference of the squared sum of intensity differences between the transformed/untransformed and the reference volume both at the 0.05 (p {\textgreater} 0.05) confidence level and an average 31\% improvement of the correlation coefficient and cross correlation. For the two-dimensional/three-dimensional method, {ROI} center-to-center distance ranged from 1.42 to 11.32 mm (for liver) with an average of 6.13 mm +/- 3.09 mm. The average {ROI} overlap was 92.51\% with a 95\% confidence interval of 90.20-96.88\%. The new method is superior because it operates on the true three-dimensional volume. Both methods give good registration results, take 10 to 30 min, and require anatomic knowledge.

Place, publisher, year, edition, pages
2001. Vol. 25, no 5, 297-307 p.
Keyword [en]
Humans, Imaging, {Three-Dimensional}, Magnetic Resonance Imaging, Neoplasms, Radiography, Abdominal, Radiography, Thoracic, Tomography, {Emission-Computed}, {Single-Photon}, Tomography, {X-Ray} Computed
National Category
Medical and Health Sciences
Research subject
URN: urn:nbn:se:kth:diva-46753DOI: 10.1023/A:1010633123512PubMedID: 11508903OAI: diva2:454135
QC 20111107Available from: 2011-11-05 Created: 2011-11-05 Last updated: 2013-09-09Bibliographically approved

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