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Hepatic hemangiomas: diagnosis with fusion of MR, CT, and Tc-99m-labeled red blood cell SPECT images
New York University.
New York University.
New York University.
New York University.
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1991 (English)In: Radiology, ISSN 0033-8419, E-ISSN 1527-1315, Vol. 181, no 2, 469-474 p.Article in journal (Refereed) Published
Abstract [en]

A method of image analysis was developed for correlation of hemangiomas detected at computed tomography {(CT)} and/or magnetic resonance {(MR)} imaging with increased blood pool activity evident at single photon emission {CT} {(SPECT)} performed after labeling of red blood cells with technetium-99m. Image analysis was performed in 20 patients with 35 known hepatic hemangiomas. After section thickness and pixel sizes of the different studies were matched, intrinsic landmarks were chosen to identify anatomically corresponding locations. Regions of interest {(ROIs)} drawn on the {CT} and/or {MR} images were translated, rotated, and reprojected to match the areas of interest on the corresponding {SPECT} images by means of a two-dimensional polynomial-based warping algorithm. Analysis of {ROIs} on 30 {SPECT-MR} and 20 {SPECT-CT} pairs of registered images provided absolute confirmation that 34 suspected hemangiomas identified on {SPECT} images correlated exactly with lesions seen on {CT} and/or {MR} images. Accuracy of fusion was within an average of 1.5 pixels +/- 0.8 (+/- 1 standard deviation). The technique enabled diagnostic confirmation of hemangiomas as small as 1.0 cm and proved useful for evaluating lesions located adjacent to intrahepatic vessels.

Place, publisher, year, edition, pages
Radiological Society of North America , 1991. Vol. 181, no 2, 469-474 p.
Keyword [en]
Adult, Aged, Erythrocytes, Female, Hemangioma, Humans, Image Processing, {Computer-Assisted}, Liver, Liver Neoplasms, Magnetic Resonance Imaging, Male, Middle Aged, Tomography, {Emission-Computed}, {Single-Photon}, Tomography, {X-Ray} Computed
National Category
Radiology, Nuclear Medicine and Medical Imaging
Research subject
URN: urn:nbn:se:kth:diva-46785ISI: A1991GL84100028OAI: diva2:454187
QC 20111107. PMID: 1924790Available from: 2011-11-06 Created: 2011-11-06 Last updated: 2013-09-09Bibliographically approved

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Maguire Jr., Gerald Q.
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